The Three-spot (Threespot, Three Spot, Frederic's) Leporinus is native to fast-flowing or moderate waters of the Amazon and Orinoco Basins and Guyana Shield. It usually shows three black spots on each flank but can show a fourth (less distinct, above right) or more small spots. It grows to 40cm long.

Some appear to have only one spot and some appear spotless. Like the Striped Leporinus, it gathers in large shoals. It eats mainly fruit, seeds and termites.

Several Leporinus species, including those above, have claim to the "lipstick" name with bright red around the chin, but this one was awarded the name Lipstick Leporinus. It is native to the Guyana Shield river systems including the Orinoco, Essequibo and parts of the Amazon tributaries. Like other Leporinus, it swims fast against strong currents and leaps well out of the water, allowing it to reach upstream spawning sites. It grows to some 25-30cm long. Its tweezer-like teeth let it pull algae from rocks on the river bed.